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Sickle Cell Anemia

Describes sickle cell anemia, including the history of the disease, how it is treated, and the current medical research towards finding a cure.

Describes sickle cell anemia, including the history of the disease, how it is treated, and the current medical research towards finding a cure.

Analysis of the drivers of change in women’s anemia in Tanzania 2005-2015

Although the prevalence of anemia among women of reproductive age in Tanzania remains high, there have been documented improvements. It declined from 47.2% in 2004-05 to 40.1% 2010, but by 2016 it has risen again to 44.8%, according to the nationally representative Demographic and Health Surveys from those years. Women’s anemia can lead to many detrimental consequences, including decreased work productivity, mortality, postpartum hemorrhage, and adverse birth outcomes. Thus, it is important to document the factors that may have contributed to improvements in anemia status. Using a regression decomposition approach, which previously has been applied to identifying potential drivers of changes in stunting, we examine which improvements in the underlying determinants of anemia contributed to improvements in the overall prevalence of anemia among women of reproductive age in Tanzania. This study is the first known application of this methodology to understanding changes in the prevelance of anemia. Among all adult women, the largest contributers of change from factors we could include in our models were increases in wealth and education, use of hormonal contraceptives, and the decrease in the proportion of women who are currently pregnant or postpartum (i.e., from the decrease in fertility rates). Notably, use of hormonal contraceptives was least common among the poorest quintile. Additionally, change was attributable to reductions in infection, specifically fever and improvements in open defecation. Among older adolescent girls (15-19 years), the largest share in the improvements in anemia were attributable to education and wealth increases. Among postpartum women, we were limited by the sample size, but found that attending all four antenatal care visits and being administered medications to prevent malaria during pregnancy were important determinants of improved hemoglobin levels.

Although the prevalence of anemia among women of reproductive age in Tanzania remains high, there have been documented improvements.

World Clinics in Obstetrics and Gynecology: Anemia

Volume 6, Number 2

Part of the World Clinics: Obstetrics & Gynecology series, this new volume presents clinicians and trainees with the latest developments in the diagnosis and management of anaemia. Beginning with an introduction to the classification, pathology and diagnosis of the condition, the following chapters cover different types of anaemia including iron deficiency, folic acid and Vitamin B12 deficiency, haemolytic, aplastic, sickle cell, and more. The book concludes with discussion on special situations such as severe anaemia in labour and antepartum haemorrhage. Presented as a collection of evidence-based reviews, each article is enhanced by photographs and figures, and concludes with a summary and comments by the editors highlighting their own clinical experience. Other volumes in the series include: Endometriosis, Polycystic Ovary Syndrome, Recurrent Miscarriage, Contraception, Ovulation Induction, Perimenopausal Health, Postpartum Hemorrhage, Preeclampsia, and Preterm Labor. Key points Latest volume in the World Clinics: Obstetrics & Gynecology series Covers diagnosis and management of different types of anaemia Each article concludes with a summary and comments by the editors Enhanced by photographs and figures throughout

Part of the World Clinics: Obstetrics & Gynecology series, this new volume presents clinicians and trainees with the latest developments in the diagnosis and management of anaemia.

Anemia, An Issue of Medical Clinics of North America, E-Book

This issue of Medical Clinics, guest edited by Dr. Thomas G. DeLoughery, is devoted to anemia. Articles in this issue include: Anemia: Evaluation and Diagnostic Tests; Anemia of Chronic Disease; B12/Folate Deficiency; Iron Deficiency; Myelodysplasia; Autoimmune Hemolytic Anemia; Congenital Hemolytic Anemia; Sickle Cell Disease; Thrombotic Microangiopathy; Unusual Anemias; and Transfusion Therapy.

This issue of Medical Clinics, guest edited by Dr. Thomas G. DeLoughery, is devoted to anemia.

Anemia

Prevalence, Risk Factors and Management Strategies

Anaemia is defined as the decrease in haemoglobin from normal values either by loss of red blood cells or deficit in production or both. Haemoglobin is the major transporter of oxygen. The variation in haemoglobin is therefore a factor in determining the cardiac output. This book begins by discussing the effects anaemia has on heart diseases. The book then continues to discuss the influence of iron deficiency anaemia and recovery on oxidative/antioxidant status; influence of iron deficiency anaemia on bone metabolism; sickle cell anaemia; anaemia in myelodysplastic syndromes; transfusion in chronic anaemia; the prevalence, risk factors and management with a focus on chronic kidney disease; strategy for treating anaemia in chronic kidney disease patients from the standpoint of iron utility; and parasitic anaemia.

Haemoglobin is the major transporter of oxygen. The variation in haemoglobin is therefore a factor in determining the cardiac output. This book begins by discussing the effects anaemia has on heart diseases.

Sickle Cell Anemia

From Basic Science to Clinical Practice

Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated with the disease. Our knowledge regarding sickle cell disease mechanisms, while still not complete, has broadened considerably over the last decades. Sickle Cell Anemia: From Basic Science to Clinical Practice aims to provide an update on our current understanding of the disease’s pathophysiology and use this information as a basis to discuss its manifestations in childhood and adulthood. Current therapies and prospects for the development of new approaches for the management of the disease are also covered.

Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood.

Anemia in the Elderly

Anemia in the elderly, known as the silent epidemic, afflicts 3 million people in the U.S. ages 65 or older. This reference, complete with the most recent findings, answers all the crucial questions regarding anemia in the elderly.

When should the suspicion for Myelodysplastic Syndrome be ruled out and what are the clues? This book addresses these and many other important questions with a review of the most recent findings.

Aplastic Anemia

Pathophysiology and Treatment

Comprehensive and up-to-date clinical reference, with an emphasis on treatment.

Comprehensive and up-to-date clinical reference, with an emphasis on treatment.

Aplastic Anemia: New Insights for the Healthcare Professional: 2013 Edition

ScholarlyBrief

Aplastic Anemia: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Genetics in a concise format. The editors have built Aplastic Anemia: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Genetics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Aplastic Anemia: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The editors have built Aplastic Anemia: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Genetics in this book to be deeper than what you ...

Iron Deficiency Anemia

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This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations.